منابع مشابه
Drug addiction.
N Engl J Med 2003;349:975-86. Copyright © 2003 Massachusetts Medical Society. rug addiction is a chronic, relapsing disorder in which compulsive drug-seeking and drug-taking behavior persists despite serious negative consequences. Addictive substances induce pleasant states (euphoria in the initiation phase) or relieve distress. Continued use induces adaptive changes in the central nervous syst...
متن کاملDrug addiction.
Psychogenic dependence is the common denominator of all drug habits and the primary drive which leads to initiation and relapse to chronic drug use or abuse (25). Although a pharmacologic drive is necessary it does not need to be a strong one or to produce profound subjective effects in order that habituation to the use of the crude material becomes a pattern of life. Besides tobacco, the use o...
متن کاملIACUC perspective on drug addiction research.
2011 379 T he articles in this issue provide an excellent overview of the breadth of research relevant to drug addiction and the key role that preclinical research has played in advancing understanding of the processes that underlie substance use and dependence disorders, as they are coded and classifi ed in the Diagnostic and Statistical Manual of Mental Disorders (4 th ed., DSM-IV; APA 1994)....
متن کاملGenetics’ Influence on Drug Abuse & Addiction Interactions of Endophenotypes & Genotypes
A B S T R A C T “Addiction” is a multifaceted complicated disorder with many interrelated causes, as well as environmental and genetic features. Several hereditary variables that have an effect on these features might work in together to influence vulnerability and the extent of being an addict. Molecular re-sequencing of the latest and formerly researched genes holds a crucial place with regar...
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ژورنال
عنوان ژورنال: Nature
سال: 1964
ISSN: 0028-0836,1476-4687
DOI: 10.1038/203445a0